Thrombophilia and Dental Surgery: A Report of Dental Extraction in a Patient with Protein S Deficiency

From Volume 27, Issue 6, July 2000 | Pages 302-305

Authors

St J. Crean

FDS RCS, FRCS (Eng.)

Lecturer, Department of Maxillofacial Surgery, Eastman Dental Institute, London

Articles by St J. Crean

V. Sivarajasingam

BSc, FDS RCS

Specialist Registrar, Dental School, University Hospital of Wales, Cardiff

Articles by V. Sivarajasingam

J. Muhammed

FDS RCS, FRCS (Edin.), FRCS (Eng.)

Specialist Registrar, Dental School, University Hospital of Wales, Cardiff

Articles by J. Muhammed

V. Sharma

BSc, BDS

House Officer, Dental School, University Hospital of Wales, Cardiff

Articles by V. Sharma

M. Fardy

FFD, RCSI, FRCS (Edin.)

Consultant, Department of Maxillofacial Surgery, Dental School, University Hospital of Wales, Cardiff

Articles by M. Fardy

Abstract

Most patients with thrombophilia are asymptomatic. A case is presented here of a young woman with protein S deficiency, one of the thrombophilias, who required dental extraction. Protein S deficiency predisposes a very small number of those affected to life-threatening thromboses and emboli, for which they are required to take lifelong prophylactic anticoagulation. This report emphasizes the need to liaise closely with haematology departments when deciding whether heparinization is required for patients already taking warfarin. The role of low-molecular-weight heparins is highlighted, a brief review of thrombophilia is given and the management of patients who are taking warfarin and need dental surgery is discussed.

Article

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